If your dog had a tumor like this the vets would just shake their heads and put him to sleep. The design follows the logic of cancer: invade and overwhelm the host organism.
The current (as of this writing; sometime in January it will be archived) Eyesore is actually a bit of positive comment on the downtown core in Troy, NY. We here in Buffalo might consider such.
* On Gehry: the first time I saw photos of a Gehry building, I thought it was really cool. Next time, still cool but obviously recycling the idea of the last one. And so on, until now I wonder if the guy has any ideas at all beyond the "crumpled tin foil ball" thing.